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Oxygen Reactivity in Flavoenzymes: Context Matters

Many flavoenzymes – oxidases and monooxygenases – react faster with oxygen than free flavins do. There are many ideas on how enzymes cause this. Recent work has focused on the importance of a positive charge near N5 of the reduced flavin. Fructosamine oxidase has a lysine near N5 of its flavin. We m...

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Detalhes bibliográficos
Main Authors: McDonald, Claudia A., Fagan, Rebecca L., Collard, François, Monnier, Vincent M., Palfey, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203534/
https://ncbi.nlm.nih.gov/pubmed/21958058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2081873
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