Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2(−/−) but not in jnk1(−/−) Mice

Lignende værker

• CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
  af: Cederbaum, Arthur I., et al.
  Udgivet: (2012)
• Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity : role of CYP2E1 and TNF-α and activation of JNK and p38 MAP kinase
  af: Wang, Xiaodong, et al.
  Udgivet: (2009)
• Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1 induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells
  af: Yang, Lili, et al.
  Udgivet: (2011)
• CYP2E1 Potentiates Ethanol-induction of Hypoxia and HIF-1α in vivo
  af: Wang, Xiaodong, et al.
  Udgivet: (2013)
• CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction
  af: Lu, Yongke, et al.
  Udgivet: (2009)