Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1 induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells

Lignende værker

• Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2(−/−) but not in jnk1(−/−) Mice
  af: Wang, Xiaodong, et al.
  Udgivet: (2011)
• CYP2E1 Enhances Ethanol-induced Lipid Accumulation but Impairs Autophaghy in HepG2 E47 Cells
  af: Wu, Defeng, et al.
  Udgivet: (2010)
• CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
  af: Cederbaum, Arthur I., et al.
  Udgivet: (2012)
• Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK()
  af: Wu, Defeng, et al.
  Udgivet: (2013)
• The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
  af: Lu, Yongke, et al.
  Udgivet: (2007)