CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases

Παρόμοια τεκμήρια

• Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2(−/−) but not in jnk1(−/−) Mice
  ανά: Wang, Xiaodong, κ.ά.
  Έκδοση: (2011)
• Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1 induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells
  ανά: Yang, Lili, κ.ά.
  Έκδοση: (2011)
• CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction
  ανά: Lu, Yongke, κ.ά.
  Έκδοση: (2009)
• Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK()
  ανά: Wu, Defeng, κ.ά.
  Έκδοση: (2013)
• Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity : role of CYP2E1 and TNF-α and activation of JNK and p38 MAP kinase
  ανά: Wang, Xiaodong, κ.ά.
  Έκδοση: (2009)