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General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain

BACKGROUND: Clinically used general anesthetics, alone or in combination, are damaging to the developing mammalian brain. In addition to causing widespread apoptotic neurodegeneration in vulnerable brain regions, exposure to general anesthesia at the peak of synaptogenesis causes learning and memory...

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Detalhes bibliográficos
Main Authors: Sanchez, Victoria, Feinstein, Shawn D., Lunardi, Nadia, Joksovic, Pavle M., Boscolo, Annalisa, Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203321/
https://ncbi.nlm.nih.gov/pubmed/21909020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182303a63
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