General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain

BACKGROUND: Clinically used general anesthetics, alone or in combination, are damaging to the developing mammalian brain. In addition to causing widespread apoptotic neurodegeneration in vulnerable brain regions, exposure to general anesthesia at the peak of synaptogenesis causes learning and memory...

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Autores principales: Sanchez, Victoria, Feinstein, Shawn D., Lunardi, Nadia, Joksovic, Pavle M., Boscolo, Annalisa, Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203321/
https://ncbi.nlm.nih.gov/pubmed/21909020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182303a63
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