The role of tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) in mediating autophagy in myositis skeletal muscle: A potential non-immune mechanism of muscle damage

OBJECTIVE: Multinucleated cells are relatively resistant to classical apoptosis, and the factors initiating cell-death and damage in myositis are not well defined. We hypothesized that non-immune autophagic cell death may play a role in muscle fiber damage. Recent literature indicates that tumor nec...

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Autores principales: Alger, Heather M., Raben, Nina, Pistilli, Emidio, Francia, Dwight, Rawat, Rashmi, Getnet, Derese, Ghimbovschi, Svetlana, Chen, Yi-Wen, Lundberg, Ingrid E., Nagaraju, Kanneboyina
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203318/
https://ncbi.nlm.nih.gov/pubmed/21769834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30530
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