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Non-immune mechanisms of muscle damage in myositis: Role of the endoplasmic reticulum stress response and autophagy in the disease pathogenesis

PURPOSE OF REVIEW: Recent literature in inflammatory myopathies suggests that both immune (cell-mediated and humoral) and non-immune (endoplasmic reticulum (ER) stress and autophagy) mechanisms play a role in muscle fiber damage and dysfunction. This review describes these findings and discusses the...

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Detalhes bibliográficos
Main Authors: Henriques-Pons, Andrea, Nagaraju, Kanneboyina
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877394/
https://ncbi.nlm.nih.gov/pubmed/19713850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0b013e3283319265
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