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Synergistic capture of Clostridium botulinum Type A neurotoxin by scFv antibodies to novel epitopes

A non-immune library of human single chain fragment variable (scFv) antibodies displayed on Saccharomyces cerevisiae was screened for binding to the Clostridium botulinum neurotoxin serotype A binding domain [BoNT/A (H(c))] with the goal of identifying scFv to novel epitopes. To do this, an antibody...

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Autors principals: Gray, Sean A., Barr, John R., Kalb, Suzanne R., Marks, James D., Baird, Cheryl L., Cangelosi, Gerard A., Miller, Keith D., Feldhaus, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203252/
https://ncbi.nlm.nih.gov/pubmed/21538339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.23196
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