The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

BACKGROUND: GP-BAR1, a member G protein coupled receptor superfamily, is a cell surface bile acid-activated receptor highly expressed in the ileum and colon. In monocytes, ligation of GP-BAR1 by secondary bile acids results in a cAMP-dependent attenuation of cytokine generation. AIMS: To investigate...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Cipriani, Sabrina, Mencarelli, Andrea, Chini, Maria Giovanna, Distrutti, Eleonora, Renga, Barbara, Bifulco, Giuseppe, Baldelli, Franco, Donini, Annibale, Fiorucci, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203117/
https://ncbi.nlm.nih.gov/pubmed/22046243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025637
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares