The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice

BACKGROUND: Although human immunodeficiency virus (HIV)–related morbidity and mortality rates in patients treated with a combination of high active antiretroviral therapy (HAART) have declined, significant metabolic/vascular adverse effects associated with the long term use of HIV protease inhibitor...

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Autori principali: Mencarelli, Andrea, Cipriani, Sabrina, Renga, Barbara, Francisci, Daniela, Palladino, Giuseppe, Distrutti, Eleonora, Baldelli, Franco, Fiorucci, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951893/
https://ncbi.nlm.nih.gov/pubmed/20949026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013238
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