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Mechanism of Lethal Toxin Neutralization by a Human Monoclonal Antibody Specific for the PA(20) Region of Bacillus anthracis Protective Antigen

The primary immunogenic component of the currently approved anthrax vaccine is the protective antigen (PA) unit of the binary toxin system. PA-specific antibodies neutralize anthrax toxins and protect against infection. Recent research has determined that in humans, only antibodies specific for part...

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Bibliografski detalji
Glavni autori: Reason, Donald, Liberato, Justine, Sun, Jinying, Camacho, Jessica, Zhou, Jianhui
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202870/
https://ncbi.nlm.nih.gov/pubmed/22069752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3080979
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