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Mechanism of Lethal Toxin Neutralization by a Human Monoclonal Antibody Specific for the PA(20) Region of Bacillus anthracis Protective Antigen

The primary immunogenic component of the currently approved anthrax vaccine is the protective antigen (PA) unit of the binary toxin system. PA-specific antibodies neutralize anthrax toxins and protect against infection. Recent research has determined that in humans, only antibodies specific for part...

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Detalhes bibliográficos
Main Authors: Reason, Donald, Liberato, Justine, Sun, Jinying, Camacho, Jessica, Zhou, Jianhui
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202870/
https://ncbi.nlm.nih.gov/pubmed/22069752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3080979
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