Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage

The superoxide free radical (O(2)(•−)) has been viewed as a likely major contributor to aging. If this is correct, then superoxide dismutase (SOD), which removes O(2)(•−), should contribute to longevity assurance. In Caenorhabditis elegans, overexpression (OE) of the major cytosolic Cu/Zn-SOD, sod-1...

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Autors principals: Cabreiro, Filipe, Ackerman, Daniel, Doonan, Ryan, Araiz, Caroline, Back, Patricia, Papp, Diana, Braeckman, Bart P., Gems, David
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2011
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Original Contribution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202636/
https://ncbi.nlm.nih.gov/pubmed/21839827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.07.020
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