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Acetylation of the Pro-Apoptotic Factor, p53 in the Hippocampus following Cerebral Ischemia and Modulation by Estrogen

BACKGROUND: Recent studies demonstrate that acetylation of the transcription factor, p53 on lysine(373) leads to its enhanced stabilization/activity and increased susceptibility of cells to stress. However, it is not known whether acetylation of p53 is altered in the hippocampus following global cer...

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Autors principals: Raz, Limor, Zhang, Quan-guang, Han, Dong, Dong, Yan, De Sevilla, Liesl, Brann, Darrell W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202599/
https://ncbi.nlm.nih.gov/pubmed/22046440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027039
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