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Extranuclear Estrogen Receptors Mediate the Neuroprotective Effects of Estrogen in the Rat Hippocampus

BACKGROUND: 17β-estradiol (E2) has been implicated to exert neuroprotective effects in the brain following cerebral ischemia. Classically, E2 is thought to exert its effects via genomic signaling mediated by interaction with nuclear estrogen receptors. However, the role and contribution of extranucl...

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Главные авторы: Yang, Li-cai, Zhang, Quan-Guang, Zhou, Cai-feng, Yang, Fang, Zhang, Yi-dong, Wang, Rui-min, Brann, Darrell W.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866326/
https://ncbi.nlm.nih.gov/pubmed/20479872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009851
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