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Cryo-reconstructions of P22 polyheads suggest that phage assembly is nucleated by trimeric interactions among coat proteins

Bacteriophage P22 forms an isometric capsid during normal assembly, yet when the coat protein (CP) is altered at a single site, helical structures (polyheads) also form. The structures of three distinct polyheads obtained from F170L and F170A variants were determined by cryo-reconstruction methods....

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Autores principales: Parent, Kristin N, Sinkovits, Robert S, Suhanovsky, Margaret M, Teschke, Carolyn M, Egelman, Edward H, Baker, Timothy S
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202341/
https://ncbi.nlm.nih.gov/pubmed/21149969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/7/4/045004
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