Anion interactions with CFTR and consequences for HCO3- transport in secretory epithelia.

We have been studying CFTR channels in guinea pig pancreatic duct cells and rather surprisingly found that luminal HCO3- had a pronounced inhibitory effect on cAMP-activated CFTR chloride currents. The block produced by HCO3- was rapid, voltage-independent and occurred over a physiological range of...

Full description

Saved in:
Bibliographic Details
Main Authors: Gray, M, O'Reilly, C, Winpenny, J, Argent, B
Format: Artigo
Language:Inglês
Published: Korean Academy of Medical Sciences 2000
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202183/
https://ncbi.nlm.nih.gov/pubmed/10981498
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items