Anion interactions with CFTR and consequences for HCO3- transport in secretory epithelia.

We have been studying CFTR channels in guinea pig pancreatic duct cells and rather surprisingly found that luminal HCO3- had a pronounced inhibitory effect on cAMP-activated CFTR chloride currents. The block produced by HCO3- was rapid, voltage-independent and occurred over a physiological range of...

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Bibliografiset tiedot
Päätekijät: Gray, M, O'Reilly, C, Winpenny, J, Argent, B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Korean Academy of Medical Sciences 2000
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202183/
https://ncbi.nlm.nih.gov/pubmed/10981498
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