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Is CFTR an exchanger?: Regulation of HCO(3)(−)Transport and extracellular pH by CFTR

The disease, cystic fibrosis, is caused by the malfunction of the cystic fibrosis transmembrane conductance regulator. Expression of functional CFTR may normally regulate extracellular pH via control of bicarbonate efflux. Reports also suggest that the CFTR may be a Cl-/HCO3- exchanger. If true, thi...

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Bibliografski detalji
Izdano u:Biochem Biophys Rep
Glavni autori: Massey, Marija K., Reiterman, Michael J., Mourad, Jad, Luckie, Douglas B.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758359/
https://ncbi.nlm.nih.gov/pubmed/33376814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100863
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