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Is CFTR an exchanger?: Regulation of HCO(3)(−)Transport and extracellular pH by CFTR

The disease, cystic fibrosis, is caused by the malfunction of the cystic fibrosis transmembrane conductance regulator. Expression of functional CFTR may normally regulate extracellular pH via control of bicarbonate efflux. Reports also suggest that the CFTR may be a Cl-/HCO3- exchanger. If true, thi...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Massey, Marija K., Reiterman, Michael J., Mourad, Jad, Luckie, Douglas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758359/
https://ncbi.nlm.nih.gov/pubmed/33376814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100863
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