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High CJD infectivity remains after prion protein is destroyed
The hypothesis that host prion protein (PrP) converts into an infectious prion form rests on the observation that infectivity progressively decreases in direct proportion to the decrease of PrP with proteinase K (PK) treatment. PrP that resists limited PK digestion (PrP-res, PrP(sc)) has been assume...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202053/ https://ncbi.nlm.nih.gov/pubmed/21793041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23286 |
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