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Proliferative arrest of neural cells induces prion protein synthesis, nanotube formation and cell-to-cell contacts

Host prion protein (PrP) is most abundant in neurons where its functions are unclear. PrP mRNA transcripts accumulate at key developmental times linked to cell division arrest and terminal differentiation. We sought to find if proliferative arrest was sufficient to cause an increase in PrP in develo...

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Autores principales: Miyazawa, Kohtaro, Emmerling, Kaitlin, Manuelidis, Laura
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930104/
https://ncbi.nlm.nih.gov/pubmed/20518071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22723
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