Reconstitution of a functional IS608 single-strand transpososome: role of non-canonical base pairing

Single-stranded (ss) transposition, a recently identified mechanism adopted by members of the widespread IS200/IS605 family of insertion sequences (IS), is catalysed by the transposase, TnpA. The transposase of IS608, recognizes subterminal imperfect palindromes (IP) at both IS ends and cleaves at s...

Full description

Saved in:
Bibliographic Details
Main Authors: He, Susu, Hickman, Alison B., Dyda, Fred, Johnson, Neil P., Chandler, Michael, Ton-Hoang, Bao
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201880/
https://ncbi.nlm.nih.gov/pubmed/21745812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr566
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items