Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation

RNA structure plays a fundamental role in internal initiation of translation. Picornavirus internal ribosome entry site (IRES) are long, efficient cis-acting elements that recruit the ribosome to internal mRNA sites. However, little is known about long-range constraints determining the IRES RNA stru...

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Detalhes bibliográficos
Main Authors: Fernández, Noemí, Fernandez-Miragall, Olga, Ramajo, Jorge, García-Sacristán, Ana, Bellora, Nicolás, Eyras, Eduardo, Briones, Carlos, Martínez-Salas, Encarnación
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201876/
https://ncbi.nlm.nih.gov/pubmed/21742761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr560
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