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Structural organization of a viral IRES depends on the integrity of the GNRA motif
Little is known about the tertiary structure of internal ribosome entry site (IRES) elements. The central domain of foot-and-mouth disease (FMDV) IRES, named 3 or I, contains a conserved GNRA motif, essential for IRES activity. We have combined functional analysis with RNA probing to define its stru...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2003 by RNA Society
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1287055/ https://ncbi.nlm.nih.gov/pubmed/14561883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5950603 |
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