Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization

Hematopoietic stem cells (HSCs) are maintained in a specific bone marrow (BM) niche in cavities formed by osteoclasts. Osteoclast-deficient mice are osteopetrotic and exhibit closed BM cavities. Osteoclast activity is inversely correlated with hematopoietic activity; however, how osteoclasts and the...

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Hlavní autoři: Miyamoto, Kana, Yoshida, Shigeyuki, Kawasumi, Miyuri, Hashimoto, Kazuaki, Kimura, Tokuhiro, Sato, Yuiko, Kobayashi, Tami, Miyauchi, Yoshiteru, Hoshi, Hiroko, Iwasaki, Ryotaro, Miyamoto, Hiroya, Hao, Wu, Morioka, Hideo, Chiba, Kazuhiro, Kobayashi, Takashi, Yasuda, Hisataka, Penninger, Josef M., Toyama, Yoshiaki, Suda, Toshio, Miyamoto, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201203/
https://ncbi.nlm.nih.gov/pubmed/22006978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101890
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