The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

CD4(+) regulatory T cells (T(reg) cells) expressing the transcription factor Foxp3 play a pivotal role in maintaining peripheral tolerance by inhibiting the expansion and function of pathogenic conventional T cells (T(conv) cells). In this study, we show that a locus on rat chromosome 9 controls the...

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Bibliographic Details
Main Authors: Colacios, Céline, Casemayou, Audrey, Dejean, Anne S., Gaits-Iacovoni, Frédérique, Pedros, Christophe, Bernard, Isabelle, Lagrange, Dominique, Deckert, Marcel, Lamouroux, Lucille, Jagodic, Maja, Olsson, Tomas, Liblau, Roland S., Fournié, Gilbert J., Saoudi, Abdelhadi
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
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Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201202/
https://ncbi.nlm.nih.gov/pubmed/21948080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20102191
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