טוען...
DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice
In humans, DOCK8 immunodeficiency syndrome is characterized by severe cutaneous viral infections. Thus, CD8 T cell function may be compromised in the absence of DOCK8. In this study, by analyzing mutant mice and humans, we demonstrate a critical, intrinsic role for DOCK8 in peripheral CD8 T cell sur...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201196/ https://ncbi.nlm.nih.gov/pubmed/22006977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110345 |
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