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DRiPs Solidify: Progress in Understanding Endogenous MHC Class I Antigen Processing

Defective Ribosomal Products (DRiPs) are a subset of rapidly degraded polypeptides that provide peptide ligands for MHC class I molecules. Here, I review recent progress in understanding DRiP biogenesis. These findings place DRiPs at the center of the MHC class I antigen processing pathway, linking...

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Autor Principal: Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200450/
https://ncbi.nlm.nih.gov/pubmed/21962745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.08.001
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