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Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
Prostaglandin E(2) (PGE(2)) triggers a vast array of biological signals and physiological events. The prostaglandin transporter (PGT) controls PGE(2) influx and is rate-limiting for PGE(2) metabolism and signaling termination. PGT global knockout mice die on postnatal day 1 from patent ductus arteri...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199986/ https://ncbi.nlm.nih.gov/pubmed/21849625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.181354 |
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