Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

Neurons in the mammalian neocortex arise from asymmetric divisions of progenitors residing in the ventricular zone. While in most progenitor divisions, the mitotic spindle is parallel to the ventricular surface, some progenitors reorient the spindle and divide in oblique orientations. Here, we use c...

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Main Authors: Postiglione, Maria Pia, Jüschke, Christoph, Xie, Yunli, Haas, Gerald A., Charalambous, Christoforos, Knoblich, Juergen A.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199734/
https://ncbi.nlm.nih.gov/pubmed/22017987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.09.022
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