Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line.
From a hybrid mouse cell line (B1-8) that secreted an IgM, lambda 1 anti-(4-hydroxy-3-nitrophenyl)acetyl antibody but that had no detectable surface IgM, selection for a variant with lambda 1 chains on the surface resulted in the isolation of a line that had switched from mu to delta expression. The...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1138 |
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