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Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line.

From a hybrid mouse cell line (B1-8) that secreted an IgM, lambda 1 anti-(4-hydroxy-3-nitrophenyl)acetyl antibody but that had no detectable surface IgM, selection for a variant with lambda 1 chains on the surface resulted in the isolation of a line that had switched from mu to delta expression. The...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Neuberger, M S, Rajewsky, K
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1981
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1138
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