Stalk Domain of the Dynamin-like MxA GTPase Protein Mediates Membrane Binding and Liposome Tubulation via the Unstructured L4 Loop

The human MxA protein is an interferon-induced large GTPase with antiviral activity against a wide range of viruses, including influenza viruses. Recent structural data demonstrated that MxA oligomerizes into multimeric filamentous or ring-like structures by virtue of its stalk domain. Here, we show...

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Bibliografiske detaljer
Main Authors: von der Malsburg, Alexander, Abutbul-Ionita, Inbal, Haller, Otto, Kochs, Georg, Danino, Dganit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199527/
https://ncbi.nlm.nih.gov/pubmed/21900240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.249037
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