Sources of Cell-to-cell Variability in Canonical Nuclear Factor-κB (NF-κB) Signaling Pathway Inferred from Single Cell Dynamic Images

The canonical nuclear factor-κB (NF-κB) signaling pathway controls a gene network important in the cellular inflammatory response. Upon activation, NF-κB/RelA is released from cytoplasmic inhibitors, from where it translocates into the nucleus, subsequently activating negative feedback loops produci...

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Bibliografiske detaljer
Main Authors: Kalita, Mridul K., Sargsyan, Khachik, Tian, Bing, Paulucci-Holthauzen, Adriana, Najm, Habib N., Debusschere, Bert J., Brasier, Allan R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199517/
https://ncbi.nlm.nih.gov/pubmed/21868381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.280925
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