Molecular Basis of the γ-Aminobutyric Acid A Receptor α3 Subunit Interaction with the Clustering Protein Gephyrin

The multifunctional scaffolding protein gephyrin is a key player in the formation of the postsynaptic scaffold at inhibitory synapses, clustering both inhibitory glycine receptors (GlyRs) and selected GABA(A) receptor (GABA(A)R) subtypes. We report a direct interaction between the GABA(A)R α3 subuni...

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Autori principali: Tretter, Verena, Kerschner, Bernd, Milenkovic, Ivan, Ramsden, Sarah L., Ramerstorfer, Joachim, Saiepour, Leila, Maric, Hans-Michael, Moss, Stephen J., Schindelin, Hermann, Harvey, Robert J., Sieghart, Werner, Harvey, Kirsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199513/
https://ncbi.nlm.nih.gov/pubmed/21880742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.291336
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