The Residence Time of GABA(A)Rs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin

The majority of fast synaptic inhibition in the brain is mediated by benzodiazepine-sensitive α1-subunit-containing GABA type A receptors (GABA(A)Rs); however, our knowledge of the mechanisms neurons use to regulate their synaptic accumulation is rudimentary. Using immunoprecipitation, we demonstrat...

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Päätekijät: Mukherjee, Jayanta, Kretschmannova, Karla, Gouzer, Geraldine, Maric, Hans-Michael, Ramsden, Sarah, Tretter, Verena, Harvey, Kirsten, Davies, Paul A., Triller, Antoine, Schindelin, Hermann, Moss, Stephen J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2011
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202462/
https://ncbi.nlm.nih.gov/pubmed/21994384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2001-11.2011
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