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The Residence Time of GABA(A)Rs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin
The majority of fast synaptic inhibition in the brain is mediated by benzodiazepine-sensitive α1-subunit-containing GABA type A receptors (GABA(A)Rs); however, our knowledge of the mechanisms neurons use to regulate their synaptic accumulation is rudimentary. Using immunoprecipitation, we demonstrat...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202462/ https://ncbi.nlm.nih.gov/pubmed/21994384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2001-11.2011 |
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