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Gephyrin-mediated γ-Aminobutyric Acid Type A and Glycine Receptor Clustering Relies on a Common Binding Site

Gephyrin is the major protein determinant for the clustering of inhibitory neurotransmitter receptors. Earlier analyses revealed that gephyrin tightly binds to residues 398–410 of the glycine receptor β subunit (GlyR β) and, as demonstrated only recently, also interacts with GABA(A) receptors (GABA(...

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Auteurs principaux: Maric, Hans-Michael, Mukherjee, Jayanta, Tretter, Verena, Moss, Stephen J., Schindelin, Hermann
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234978/
https://ncbi.nlm.nih.gov/pubmed/22006921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303412
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