Analysis of Two Major Intracellular Phospholipases A(2) (PLA(2)) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA(2)α, Not Ca(2+)-independent PLA(2)β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts

Mast cells release a variety of mediators, including arachidonic acid (AA) metabolites, to regulate allergy, inflammation, and host defense, and their differentiation and maturation within extravascular microenvironments depend on the stromal cytokine stem cell factor. Mouse mast cells express two m...

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Main Authors: Ueno, Noriko, Taketomi, Yoshitaka, Yamamoto, Kei, Hirabayashi, Tetsuya, Kamei, Daisuke, Kita, Yoshihiro, Shimizu, Takao, Shinzawa, Koei, Tsujimoto, Yoshihide, Ikeda, Kazutaka, Taguchi, Ryo, Murakami, Makoto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199472/
https://ncbi.nlm.nih.gov/pubmed/21880721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290312
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