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Analysis of Two Major Intracellular Phospholipases A(2) (PLA(2)) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA(2)α, Not Ca(2+)-independent PLA(2)β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts
Mast cells release a variety of mediators, including arachidonic acid (AA) metabolites, to regulate allergy, inflammation, and host defense, and their differentiation and maturation within extravascular microenvironments depend on the stromal cytokine stem cell factor. Mouse mast cells express two m...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199472/ https://ncbi.nlm.nih.gov/pubmed/21880721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290312 |
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