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Characterization of Cholix Toxin-induced Apoptosis in HeLa Cells

Cholix toxin (Cholix) is a novel ADP-ribosylating cytotoxin produced by Vibrio cholerae, which utilizes eukaryotic elongation factor 2 as a substrate and acts by a mechanism similar to that of diphtheria toxin and Pseudomonas exotoxin A. First it was found that Cholix-treated HeLa cells exhibited ca...

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Detalhes bibliográficos
Main Authors: Ogura, Kohei, Yahiro, Kinnosuke, Tsutsuki, Hiroyasu, Nagasawa, Sayaka, Yamasaki, Shinji, Moss, Joel, Noda, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199468/
https://ncbi.nlm.nih.gov/pubmed/21903588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246504
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