A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function and lifespan in Drosophila

Molecular mechanisms that concordantly regulate stress, lifespan and age-related physiological changes remain incompletely understood. Here, we demonstrate that in Drosophila, a p38 MAP Kinase (p38K)/Mef2/MnSOD pathway is a co-regulator of stress and lifespan in vivo. Hence, over-expression of p38K...

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Autors principals: Vrailas-Mortimer, Alysia, delRivero, Tania, Mukherjee, Subhas, Nag, Sanjay, Gaitanidis, Alexandros, Kadas, Dimitris, Consoulas, Christos, Duttaroy, Atanu, Sanyal, Subhabrata
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199449/
https://ncbi.nlm.nih.gov/pubmed/22014527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.09.002
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