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A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function and lifespan in Drosophila
Molecular mechanisms that concordantly regulate stress, lifespan and age-related physiological changes remain incompletely understood. Here, we demonstrate that in Drosophila, a p38 MAP Kinase (p38K)/Mef2/MnSOD pathway is a co-regulator of stress and lifespan in vivo. Hence, over-expression of p38K...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199449/ https://ncbi.nlm.nih.gov/pubmed/22014527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.09.002 |
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