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MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan

Chronological lifespan (CLS) is defined as the duration of quiescence in which normal cells retain the capacity to reenter the proliferative cycle. This study investigates whether hydroxytyrosol (HT), a naturally occurring polyphenol found in olives, extends CLS in normal human fibroblasts (NHFs). Q...

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Detalhes bibliográficos
Main Authors: Sarsour, Ehab H., Kumar, Maneesh G., Kalen, Amanda L., Goswami, Monali, Buettner, Garry R., Goswami, Prabhat C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260369/
https://ncbi.nlm.nih.gov/pubmed/21384152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9223-7
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