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Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations

[Image: see text] An efficient and broadly useful two-step ligation protocol is developed. Important mechanistic issues of ligation were probed from diastereomeric competition studies on the formation of the ligation products. We also report an instance of kinetically controlled ligation through the...

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Detalhes bibliográficos
Main Authors: Tan, Zhongping, Shang, Shiying, Danishefsky, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199326/
https://ncbi.nlm.nih.gov/pubmed/21053233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201005513
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