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An Advance in Proline Ligation

Native chemical ligation (NCL) is widely applicable for building proteins in the laboratory. Since the discovery of this method, many strategies have been developed to enhance its capability and efficiency. Because of the poor reactivity of proline thioesters, ligation at a C-terminal proline site i...

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Autors principals: Shang, Shiying, Tan, Zhongping, Dong, Suwei, Danishefsky, Samuel J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135777/
https://ncbi.nlm.nih.gov/pubmed/21696220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja204277b
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