A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis

Morphogenesis of mammalian facial processes requires coordination of cellular proliferation, migration, and apoptosis to develop intricate features. Cleft lip and/or palate (CL/P), the most frequent human craniofacial birth defect, can be caused by perturbation of any of these programs. Mutations of...

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Main Authors: Ferretti, Elisabetta, Li, Bingsi, Zewdu, Rediet, Wells, Victoria, Hebert, Jean M., Karner, Courtney, Anderson, Matthew J., Williams, Trevor, Dixon, Jill, Dixon, Michael J., Depew, Michael J., Selleri, Licia
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199312/
https://ncbi.nlm.nih.gov/pubmed/21982646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.08.005
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