Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion

Human cleft lip with or without cleft palate (CL/P) is a common craniofacial abnormality caused by impaired fusion of the facial prominences. We have previously reported that, in the mouse embryo, epithelial apoptosis mediates fusion at the seam where the prominences coalesce. Here, we show that apo...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Losa, Marta, Risolino, Maurizio, Li, Bingsi, Hart, James, Quintana, Laura, Grishina, Irina, Yang, Hui, Choi, Irene F., Lewicki, Patrick, Khan, Sameer, Aho, Robert, Feenstra, Jennifer, Vincent, C. Theresa, Brown, Anthony M. C., Ferretti, Elisabetta, Williams, Trevor, Selleri, Licia
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868993/
https://ncbi.nlm.nih.gov/pubmed/29437830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157628
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