Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme

The spleen plays critical roles in immunity and also provides a permissive microenvironment for hematopoiesis. Previous studies have reported that the TALE‐class homeodomain transcription factor Pbx1 is essential in hematopoietic stem and progenitor cells (HSPCs) for stem cell maintenance and progen...

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Bibliografiska uppgifter
I publikationen:J Anat
Huvudupphovsmän: Zewdu, Rediet, Risolino, Maurizio, Barbulescu, Alexandru, Ramalingam, Pradeep, Butler, Jason M., Selleri, Licia
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341595/
https://ncbi.nlm.nih.gov/pubmed/27075259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12479
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