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A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus

BACKGROUND & AIMS: T-helper (Th)17 cells that secrete interleukin (IL)-22 have immunomodulatory and protective properties in the liver and other tissues. IL-22 induces expression of proinflammatory genes, but is also mitogenic and anti-apoptotic in hepatocytes. Therefore, it could have multiple...

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Detalhes bibliográficos
Main Authors: Zhang, Ye, Cobleigh, Melissa A., Lian, Jian-Qi, Huang, Chang-Xing, Booth, Carmen J., Bai, Xue-Fan, Robek, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199295/
https://ncbi.nlm.nih.gov/pubmed/21708106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.051
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