Notch Signaling Contributes to Liver Inflammation by Regulation of Interleukin-22-Producing Cells in Hepatitis B Virus Infection

The mechanism of hepatitis B virus (HBV) induced liver inflammation is not fully elucidated. Notch signaling augmented interleukin (IL)-22 secretion in CD4(+) T cells, and Notch-IL-22 axis fine-tuned inflammatory response. We previously demonstrated a proinflammatory role of IL-22 in HBV infection....

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wei, Xin, Wang, Jiu-Ping, Hao, Chun-Qiu, Yang, Xiao-Fei, Wang, Lin-Xu, Huang, Chang-Xing, Bai, Xue-Fan, Lian, Jian-Qi, Zhang, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065963/
https://ncbi.nlm.nih.gov/pubmed/27800305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00132
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